Femtosecond Lasers & LASIK Studies & Articles PDF Print E-mail

IntraLase: Changing the LASIK Landscape - Though the exact cause of TLS is still uncertain, some surgeons believe that the inflammation is caused by necrotic cellular debris…

Transient light sensitivity a minor complication of IntraLase use - Some users of the IntraLase femtosecond laser keratome first noticed the complication when they began working with the system more than 2 years ago. Since then, the phenomenon has gone under multiple names.

Transient light-sensitivity syndrome after LASIK with the femtosecond laser Incidence and prevention - To describe the incidence of transient light-sensitivity syndrome (TLSS) after laser in situ keratomileusis (LASIK) with the femtosecond laser and to identify preventive strategies.

Flap folds after femtosecond LASIK - To report a case of bilateral flap folds after a laser-assisted in situ keratomileusis (LASIK) procedure in which the flap was created by the femtosecond laser.

Macular hemorrhage after laser in situ keratomileusis (LASIK) with femtosecond laser flap creation - To report the first case of macular hemorrhage following LASIK with femtosecond laser flap creation.

Refractive surgery: lessons to be learned - "Indeed the long-term problems created by laser refractive surgery are not yet a major issue, but soon will be."

Complications of refractive excimer laser surgery - A German article related to complications.

A comparative confocal microscopy analysis after LASIK with the IntraLase femtosecond laser vs Hansatome microkeratome - To evaluate and compare confocal microscopy findings between a femtosecond laser and a mechanical microkeratome.

Comparison of goblet cell density after femtosecond laser and mechanical microkeratome in LASIK - To study the effect of the LASIK procedure performed with a femtosecond laser and a manual microkeratome on the conjunctival goblet cell and epithelial cell populations.

Researchers analyze femtosecond laser bubble morphology


The size and shape of femtosecond laser bubbles do not correlate with the energy applied, a study in eye bank eyes found.

Jared Schultz


“Probably you can work with energy levels much lower than you do currently, because the levels we are using right now just cause punctual disruption of the stroma, with tissue bridges remaining in between,” he told Ocular Surgery News in an interview. “To open the dissection line, we still need to tear apart these structures.”

He said the researchers did an experimental series using power as high as 15 µJ, which created larger disruption bubbles but still did not yield a clear dissection line.

“You don’t gain better results by just going to a higher energy,” he said.

Dr. Vossmerbaeumer said that one shortcoming of the study was that it is difficult to measure the actual energy output of the laser source.

“On a research basis, it will be perhaps a question to know whether the machine really emits a 4 µJ pulse. It might be that one is a 3 µJ pulse and one is 5 µJ,” he said in the interview. “The femtosecond laser pulses are known not to be perfectly stable, so they oscillate in the energy they emit. That’s important to keep in mind when looking at all these results.”

More from another peer-reviewed journal article discussing Intralase flaps

First Clinical Results With the Femtosecond Neodynium-glass Laser in Refractive Surgery  Journal of Refractive Surgery Vol. 19 No. 2 March/April 2003  Imola Ratkay-Traub, MD, PhD; Istvan E. Ferincz, MSc; Tibor Juhasz, PhD; Ron M. Kurtz, MD; Ronald R. Krueger, MD  

"This figure suggests that the wound healing process was slower compared to conventional LASIK, and may be explained by difficulties encountered in flap elevation; in a few eyes separation of the flap from the stromal bed was not optimum."



"It was reported to intralase that subsequent to bilateral "bladeless" lasik, the pt developed severe "dlk," which was treated with long-term topical and oral steroids. Posterior subcapsular cataracts formed and intrastromal scarring resulted. Cataract surgery will be performed to prevent permanent impairment. It should be noted that the reporting physician assumed this pt's follow-up care and was not the surgeon who performed the lasik procedure. "